대학원
School of Pharmacy
교수/연구실
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문애리 | 교수 | 미)아이오와주립대(석,박사) 유전공학센터(Post Doc.) |
약품생화학 | 901-8394 | armoon@duksung.ac.kr |
| Aree Moon | Professor | Ph.D. (Iowa State University) | Biochemistry/ Molecular Oncology |
약품생화학연구실 
대표논문/연구실적 (Representative publication)
- Stabilization of lipid lamellar bilayer structure of stratum corneum modulated by poly (2-methacryloyloxyethyl phosphorylcholine) in relation to skin hydration and skin protection: Tissue Eng. Regen. Med. 18(6): 953-962, 2021. (SCIE) - URL: https://doi.org/10.1007/s13770-021-00379-4
- Dose dependent pro- or anti-scar preventing responses of freeze-dried amniotic membrane extract in relation to suppression of connective Tissue Growth Factor and a- Smooth muscle actin. J Pharm. Invest. vol. 51: 327-336, 2021. (SCIE) - URL: https://doi.org/10.1007/s40005-021-00518-y
- Microneedle-mediated delivery of cosmeceutically relevant nucleoside and peptides in human skin: challenges and strategies for dermal delivery. J Pharm. Invest. 49:587-601, 2019. (SCIE) - URL: https://doi.org/10.1007/s40005-019-00438-y
연구분야 (Research Area)
- Transdermal and dermal drug delivery/ cosmeceutically relevant nucleoside and peptides delivery system: formulation development and evaluation/ pharmacokinetics
- The role of tumor microenvironment on cancer progression
- Effect of autophagy on breast cancer progression
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조애리 | 교수 | 서울대(석사) 미)Rutgers대(박사) 미)Harvard대 의대(Post Doc.) |
약제학 | 901-8388 | aeri@duksung.ac.kr |
| Ae-Ri Cho | Professor | Rutgers University (NJ. USA). Ph.D. | Pharmaceutics/ Drug Delivery System/ Skin delivery/cosmeceutics |
생물약제학연구실
대표논문/연구실적 (Representative publication)
- Stabilization of lipid lamellar bilayer structure of stratum corneum modulated by poly (2-methacryloyloxyethyl phosphorylcholine) in relation to skin hydration and skin protection: Tissue Eng. Regen. Med. 18(6): 953-962, 2021. (SCIE) - URL: https://doi.org/10.1007/s13770-021-00379-4
- Dose dependent pro- or anti-scar preventing responses of freeze-dried amniotic membrane extract in relation to suppression of connective Tissue Growth Factor and a- Smooth muscle actin. J Pharm. Invest. vol. 51: 327-336, 2021. (SCIE) - URL: https://doi.org/10.1007/s40005-021-00518-y
- Microneedle-mediated delivery of cosmeceutically relevant nucleoside and peptides in human skin: challenges and strategies for dermal delivery. J Pharm. Invest. 49:587-601, 2019. (SCIE) - URL: https://doi.org/10.1007/s40005-019-00438-y
연구분야 (Research Area)
- Transdermal and dermal drug delivery/ cosmeceutically relevant nucleoside and peptides delivery system: formulation development and evaluation/ pharmacokinetics
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박명숙 | 교수 | 덕성여대(석,박사) 미)U.C.Berkeley대(Post Doc.) |
약품화학 | 901-8395 | mspark@duksung.ac.kr |
| Myung-Sook Park | Professor | Duksung Women’s University, Ph.D. |
Synthetic Pharmaceutical
Chemistry/ Drug Synthesis/ Development of Anticancer |
약품합성연구실
대표논문/연구실적 (Representative publication)
- Selenium-containing Bis(alkylselanyl)pyridazines: Synthesis, and Evaluation of Antiproliferative Activities, Bull. Korean Chem. Soc., 37, 2, 234-237 (2016). SCI - URL: https://doi.org/10.1002/bkcs.10635
- Synthesis and Antiproliferative Activities of Chloropyridazine Derivatives Retain Alkylsulfonyl Moiety. Bull. Korean Chem. Soc., 37, 11, 1858-1861 (2016). SCI - URL: https://doi.org/10.1002/bkcs.10967
- Synthesis and Evaluation of Novel 3-Allylseleno-6-alkylsulfonylpyridazine Derivatives with Potential Anticancer Properties. Bull. Korean Chem. Soc., 38, 11, 1327-1332 (2017). SCI - URL: https://doi.org/10.1002/bkcs.11292
연구분야 (Research Area)
- Organicselenium Compounds/ Antiproliferative/ New Pyridazines
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신혜순 | 교수 | 덕성여대(석,박사) 미)Washington대(Post Doc.) |
약품미생물학,감염미생물학 | 901-8398 | 901-8398 |
| Hea Soon Shin | Professor | Duksung Women’s University, Ph.D. |
Life Pharmacy/ Medical Microbiology |
약품미생물학 연구실 (Pharmaceutical Microbiology)
장마이크로바이옴의 미생물에 대한 항생효과를 탐구하는 연구실입니다.
- 1) Antibacterial effects - Postprobiotics로서 항균효과 작용기전 규명
- 2) Antiviral effects - Lactobacillus, Bifodobacterium의 항바이러스 효과 연구
- 3) Antiinflammatory effects - Probiotics로서 항염증 효과 분석 연구
- 4) Immunomodulatory effects - Chemokine, Cytokine 등의 발현 변화 분석 연구
대표논문/연구실적 (Representative publication)
- Antimicrobial and immunomodulatory effects of Bifidobacterium strains : SCIE Scopus KCI dColl. - URL: https://www.jmb.or.kr/main.html
- Antibacterial effect of eight probiotic strains of Bifidobacterium against pathogenic Staphylococcus aureus and Pseudomonas aeruginosa : SCIE Scopus KCI dColl. - URL: https://www.ksov.org/main.html
- Anti-rotaviral and chemokine upregulation effect of Caco-2 cells induced sonicated-Lactobacillus ruminis and Bifidobacterium longum : SCIE Scopus KCI dColl. - URL: http://www.msk.or.kr/main.html
연구분야 (Research Area)
- Antimicrobial, Antiviral, Anti-inflammatory Activity and Antibiotics Sensitivity Assessment
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이용수 | 교수 | 부산대(석사) 미)Loyola Univ of Chicago(박사) |
약물학 | 901-8396 | yongslee@duksung.ac.kr |
| Yong Soo Lee | Professor | Loyola University of Chicago Medical School, Ph.D. |
pharmacology |
시스템약물학실
대표논문/연구실적 (Representative publication)
- Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells. Free Radic Res 2004 Apr;38(4):405-12. doi: 10.1080/10715760410001665262. - URL : https://doi.org/10.1080/10715760410001665262
- Diazoxide protects against hydrogen peroxide-induced toxicity in the osteoblastic MC3T3-E1 cells. Eur J Pharmacol 2009 Dec 10;624(1-3):45-50. doi: 10.1016/j.ejphar.2009.09.041. - URL : https://www.researchgate.net/publication/26838910_Diazoxide_protects_against_hydrogen_peroxide-induced_toxicity_in_the_osteoblastic_MC3T3-E1_cells
- Red ginseng supplementation more effectively alleviates psychological than physical fatigue. J Ginseng Res 2011 Sep;35(3):331-8. doi: 10.5142/jgr.2011.35.3.331. - URL : https://scienceon.kisti.re.kr/srch/selectPORSrchArticle.do?cn=JAKO201129063823650&SITE=CLICK
연구분야 (Research Area)
- pharmacology
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정인재 | 교수 | 덕성여대(석사) 미)Dartmouth대(박사) 미)Yale대(Post Doc. Associate) |
해부생리학 | 901-8381 | ijchung@duksung.ac.kr |
| Injae Chung | Professor | Dartmouth College, Ph.D. | Molecular Pharmacology |
해부생리학연구실
대표논문/연구실적 (Representative publication)
- A Proposal to Change Welfare Policy Principles for Agent Orange Exposed Korean Veterans - URL : https://doi.org/10.5668/JEHS.2014.40.2.157
- Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo - URL : https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-13-604
- Preclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites - URL : https://mct.aacrjournals.org/content/11/2/427
연구분야 (Research Area)
- CHK2 is a checkpoint kinase involved in ATM-mediated responses to DNA double-strand break (DSB). In relation to killing cancer cells, inhibition or activation of CHK2 depends on many variables such as type of DNA damaging anticancer chemicals, the genetic background of cancer cells and the specificity and efficacy of CHK2 inhibitors. CHK1 inhibitors have been found to increase the efficacy of various DNA-damaged anticancer drugs, and there are inhibitors that have been clinically tested, but there is still no agreement on selective inhibition of CHK2. We are currently evaluating potent and selective low molecular weight CHK2 inhibiting Hit chemicals as a chemosesitizer or radiosensitizer. It aims to develop strategies to enhance the effects of anticancer chemotherapy and radiation of non-small cell lung cancer (NSCLC).
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김영미 | 교수 | 덕성여대(석,박사) 미)오스틴텍사스대(Post Doc.) |
예방약학 | 901-8455 | kym123@duksung.ac.kr |
| Kim Young Mi | Professor | University of Texas at Austin | Public Healthe & Preventive Pharmacy/ Immune cell biology |
예방약학 및 독성학실
대표논문/연구실적 (Representative publication)
- Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice. Biomolecules & Therapeutics 28:456-464 - URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457176/
- Entinostat, a histone deacetylase inhibitor, increases the population of IL-10+ regulatory B cells to suppress contact hypersensitivity. BMB Rep. 54:534-539 - URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560462/
- Swertia pseudochinensis Methanol Extract Inhibits IgE-mediated Allergic Response In vitro and In vivo, Kor. J. Pharmacogn. 51(4) : 317 ∼ 324 - URL : https://doi.org/10.22889/KJP.2020.51.4.317
연구분야 (Research Area)
- Immune cell biology, Inflammation, Allergic diseases
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윤혜란 | 교수 | 서울대(석,박사) 미)Yale대 의대(Post Doc.) |
약품분석학, 약품기기분석학 | 901-8387 | hyeran11@duksung.ac.kr |
| Hye-Ran Yoon | Professor | College of Pharmacy, Seoul National University. (Ph.D.) | Pharmacy /Biomedical & Pharmaceutical Analyses |
생의약분석실
대표논문/연구실적 (Representative publication)
- Lee HJ, Yoon HR (2021) Method Development and Clinical Application of Targeted Five Omega Fatty Acids on Dried Serum Spots Using UHPLC-ESI-MS/MS. Chromatographia, in press.
- Lee HJ, Yoon HR (2021) Simultaneous Analyses of 5 Omega Fatty Acids on Dried Serum Spot using Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry. Yakhak Hoeji 65(4): 264-275. - URL : https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002754113
- Na SH, Yoon HR (2021) A Rapid and Sensitive Quantification Method of Sphingosine and Sphingosine-1-phosphate in Human Serum by Ultra High-Performance Liquid Chromatography-Tandem Mass Spectrometry. Yakhak Hoeji 65(1): 31-40. - URL : https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002690960
연구분야 (Research Area)
- Pharmacy (Biomedical and Pharmaceutical Analyses) UHPLC-MS/MS-based metabolic analyses, Metabolic profiling, Biomarker development of inflamation diseases: asthma, breast cancer, and alzheimer's disease.
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이상협 | 교수 | KAIST(석사) 미)노스캐롤라이나주립대(박사) 미)스크립스 연구소(Post Doc.) |
의약화학 | 901-8393 | sanghyup@duksung.ac.kr |
| Sang Hyup Lee | Professor | North Carolina University. Ph.D. | Pharmacy / Medicinal and Organic Chemistry |
의약화학 연구실 (Medicinal Chemistry Lab)
본 연구실은 유기화학 및 의약화학적 지식을 바탕으로 화합물 고안 및 합성을 통해 고활성물질을 발굴하고, 이를 이용하여 신약후보물질을 발굴함으로써 신약개발이라는 원대한 목표를 향해 나아가고 있는 연구실이다. 특히 파킨슨병 치료제 개발에 있어 활성산소생성 및 단백질 섬유화를 억제하는 후보물질(벤질리덴유도체)을 발굴하여 비임상연구 및 백업연구를 진행하고 있다.
그리고 항암제 연구로서 비임상후보물질(인돌유도체)를 발굴하여 후속 고안 및 합성 연구를 진행하고 있다. 또한 항균효능물질 발굴을 위해 저분자화합물 고안 및 합성을 진행하고 있다. 이러한 내용을 중심으로 국가연구기관의 지원을 바탕으로 활발한 연구를 진행하고 있다.
그리고 항암제 연구로서 비임상후보물질(인돌유도체)를 발굴하여 후속 고안 및 합성 연구를 진행하고 있다. 또한 항균효능물질 발굴을 위해 저분자화합물 고안 및 합성을 진행하고 있다. 이러한 내용을 중심으로 국가연구기관의 지원을 바탕으로 활발한 연구를 진행하고 있다.
대표논문/연구실적 (Representative publication)
- One‐Pot Synthesis of Novel Multisubstituted 1‐Alkoxyindoles. Molecules 2021, 26, 1466. - URL : https://www.mdpi.com/1420-3049/26/5/1466
- An efficient and practical method for the selective synthesis of sodium diselenide and diorganyl diselenides through selenium reduction. Tetrahedron 2020, 76, 131720. - URL : https://doi.org/10.1016/j.tet.2020.131720
- Synthesis of New 3-Substituted 1-Hydxroxy-2-Phenylindoles Using Sulfur-Containing Nucleophiles, Heterocycles. Heterocycles 2016, 92 (11), 2004-2017. - URL : http://dx.doi.org/10.3987/COM-16-13544
연구분야 (Research Area)
- [Organic Chemistry]
- - Retrosynthetic analysis and total synthesis of complex natural products
- - Design and synthesis of bioactive molecules; isolation and characterization of chiral compounds
- - Studies on sulfur-containing heterocycles
- - Indole synthesis through novel nucleophilic 1,5-additions
- [Medicinal Chemistry]
- - Sulfur/Selenium-containing molecules: design, synthesis, and biological evaluations
- - Drug activation mechanism of anticancer agents, mitomycins: mechanistic (kinetic) studies on drug activation using solvolysis reaction
- - DNA binding profiles: evaluation of the efficiency of drug to produce DNA ISC (interstrand cross-links)
- [Drug development]
- - Design, synthesis and application of small molecules for CNS diseases such as Parkinson’s disease and AD based on the imidazolidine scaffold.
- - Application of various disulfide-containing molecules as antioxidant agens
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조효선 | 교수 | 서울대(석사) 미)Texas A&M(박사) 미)펜실베니아대(Post Doc.) |
면역학 및 바이오의약품론 | 901-8678 | hyosun1102@duksung.ac.kr |
| Hyosun Cho | Professor | Texas A&M University HSC. Ph.D. | Immunology/Tumor immunology |
면역학 연구실 (Immunology Lab)
- 면역학 연구실은 덕성혁신신약센터 소속으로 진행중인 세부연구분야는 다음과 같음.
- 1) 암미세환경 및 NK세포의 상호작용 연구
- 2) RNA 바이러스에 대한 면역방어인자 연구
- 3) 마이크로바이옴 기반 항암 및 면역증강 효능 평가 연구
대표논문/연구실적 (Representative publication)
- NLRP3 Deficiency in Hepatocellular Carcinoma Enhances Surveillance of NK-92 through a Modulation of MICA/B. Lee HH, Kim D, Jung J, Kang H, Cho H. - URL : https://doi.org/10.3390/ijms22179285
- Cisplatin Resistance in Epstein–Barr-Virus-Associated Gastric Carcinoma Acquired through ATM Methylation. Lee S, Choi S, Choi W, Cho S, Cho M, Kim D, Kang B, Kim J, Lee Y, Cho H, Kang H. - URL : https://doi:org/10.3390/cancers13174252
- Induction of Multiple Immune Regulatory Pathways with Differential Impact in HCV/HIV Coinfection. Cho H, Kikuchi M, Li Y, Nakamoto N, Amorosa VK, Valiga ME, Chang KM. - URL : https://doi.org/10.3389/fimmu.2014.00265
연구분야 (Research Area)
- tumor immunology, viral immunology, natural killer cells
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정주희 | 부교수 | 덕성여대(석사) 일본 오사카대(박사) 오사카대/서울아산병원(Post Doc.) |
독성학 | 901-8731 | joohee@duksung.ac.kr |
| Joohee Jung | Associate Professor | Osaka University. Ph.D. | Env. Pharm. Sci./ Evaluation of anticancer therapeutic efficacy, xenograft model |
나노독성연구실 (Nanotoxicology Lab)
암 극복을 목표로 항암제 개발에 필요한 효능 및 독성을 평가하는 연구실입니다.
- 1) 이식암동물모델을 통한 효능평가시스템 개발
- 2) 천연물질을 활용한 항암효능 극대화 전략 모색
- 3) 성호르몬에 따른 항암효능 및 부작용 연구
대표논문/연구실적 (Representative publication)
- Advanced xenograft model with cotransplantation of patient-derived organoids and endothelial colony-forming cells for precision medicine. Journal of Oncology, 2021, 1-9, 14 July, 2021. - URL : https://doi.org/10.1155/2021/9994535
- Estrogen aggravates tumor growth in a diffuse gastric cancer xenograft model. Pathology & Oncology Research, 16 Apr, 2021. - URL : https://doi.org/10.3389/pore.2021.622733
- Upregulation of G protein-coupled estrogen receptor by chrysin-nanoparticles inhibits tumor proliferation and metastasis in triple negative breast cancer xenograft model, Front. Endo., 2020 Sep, 11, 560605, 1-11 (2020). - URL : https://www.frontiersin.org/articles/10.3389/fendo.2020.560605/full
연구분야 (Research Area)
- Env. Pharm. Sci./ Evaluation of anticancer therapeutic efficacy, xenograft model
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강규태 | 부교수 | 서울대(석사) Medical College of Georiga(박사) 미 Harvard대 의대(Post Doc.) |
약물치료학 | 901-8738 | ktkang@duksung.ac.kr |
| Kyu-Tae Kang | Associate Professor | Medical College of Georgia, Ph.D. | Vascular physiology and pharmacology |
혈관치료연구실 (Vascular Biology & Therapeutics Lab)
대표논문/연구실적 (Representative publication)
- Advanced xenograft model with cotransplantation of patient-derived organoids and endothelial colony-forming cells for precision medicine. Journal of Oncology, 2021, 1-9, 14 July, 2021. - URL : https://doi.org/10.1155/2021/9994535
- Estrogen aggravates tumor growth in a diffuse gastric cancer xenograft model. Pathology & Oncology Research, 16 Apr, 2021. - URL : https://doi.org/10.3389/pore.2021.622733
- Upregulation of G protein-coupled estrogen receptor by chrysin-nanoparticles inhibits tumor proliferation and metastasis in triple negative breast cancer xenograft model, Front. Endo., 2020 Sep, 11, 560605, 1-11 (2020). - URL : https://www.frontiersin.org/articles/10.3389/fendo.2020.560605/full
연구분야 (Research Area)
- Env. Pharm. Sci./ Evaluation of anticancer therapeutic efficacy, xenograft model
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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|---|---|---|---|---|---|---|
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한은영 | 부교수 | 서울대(석사) 서울대(박사) |
사회약학 | 901-8736 | homepage2600@duksung.ac.kr |
| Eunyoung Han | Associate Professor | Seoul National University. Ph.D. | Pharmacy/drug analysis in forensic science field |
사회약학/오남용약물연구실 (Drug Analysis Lab)
사회약학/오남용약물 연구실에서는 우리 사회에 남용되는 약물, 마약류의 남용, 마약류재활치료자에 대해 법적 및 제도적 현황 및 개선방향, 생체 시료(모발, 소변, 혈액) 중 마약류 분석법 및 유효성을 연구한다. 또한, 식품, 수산물, 한약재, 유역수 중 오염물질, 잔류물질, 마약류 분석 연구를 진행한다.
대표논문/연구실적 (Representative publication)
- Development of an Analytical Method for Detection of Anesthetics and Sedatives in Fish. Hong S, Kwon N, Kang HS, Jang E, Kim H, Han E. J AOAC Int. 2021 Dec 11:qsab155. - URL : https://academic.oup.com/jaoac/advance-article-abstract/doi/10.1093/jaoacint/qsab155/6459651?redirectedFrom=fulltext
- Development of a LC-MS/MS method for determination of propofol-glucuronide in hair and preliminary study on relationships between dose and hair concentration. Kwon NJ, Kim HJ, Cho S, Lee MA, Han E. Forensic Sci Int. 2020 Jan;306:110070. - URL : https://www.sciencedirect.com/science/article/abs/pii/S0379073819304827?via%3Dihub
- Concentrations of THC, CBD, and CBN in commercial hemp seeds and hempseed oil sold in Korea. Jang E, Kim H, Jang S, Lee J, Baeck S, In S, Kim E, Kim YU, Han E. Forensic Sci Int. 2020 Jan;306:110064. - URL : https://www.sciencedirect.com/science/article/abs/pii/S0379073819304761?via%3Dihub
연구분야 (Research Area)
- Drug analysis in forensic science field
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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|---|---|---|---|---|---|---|
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정우현 | 부교수 | 서울대(석사)서울대(박사) 미)MD앤더슨 암센터, Baylor 의대(Post Doc.) |
분자생물학, 신경과학 | 901-8737 | whchung23@duksung.ac.kr |
| Eunyoung Han | Associate Professor | Seoul National University. Ph.D. | Pharmacy/drug analysis in forensic science field |
분자세포생물학 실험실 (Lab of Molecular Cell Biology)
- 우리 연구실에서는 DNA 손상복구를 위해 세포가 이용하는 다양한 경로에 필요한 새로운 유전적 요구조건을 발견하고 각각의 조절 기작을 밝혀내어 외부환경 조건이나 세포의 상태에 따라 각기 다른 DNA 손상 복구 경로를 이용하게 되는 이유와 적합성을 이해하고자 연구하고자 한다. 더 나아가서는 DNA 상동 재조합 과정에서 발생하는 오류가 축적되어 유도되는 유전체 불안정화로 인한 유전적 질환에 해당하는 암이나 노화와 같은 퇴행성 질환들의 초기 발생 원인과 표적을 유전적/분자적 수준에서 밝히고자 한다. 최근에는 카페인 등의 신호전달물질에 대한 세포의 반응 및 저항성에 영향을 미치는 유전적 요인을 분석하는 연구도 진행하고 있다.
대표논문/연구실적 (Representative publication)
- Eun-Jung Kim, Yong-Joon Cho, Woo-Hyun Chung*, Jung-Hye Roe*. (2020) Regulation of sugar metabolism by Rsv1 for long-term survival in fission yeast. FEBS J. 287, 878-896. - URL : https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15052
- Ji Eun Choi, Seo-Hee Heo, Myung Ju Kim, Woo-Hyun Chung. (2018) Lack of superoxide dismutase in a rad51 mutant exacerbates genomic instability and oxidative stress-mediated cytotoxicity in Saccharomyces cerevisiae. Free Radic Biol Med. 129, 97-106. - URL : https://pubmed.ncbi.nlm.nih.gov/30223018/
- Marenda Wilson, Youngho Kwon, Yuanyuan Xu, Woo-Hyun Chung, Peter Chi, Hengyao Niu, Xuefeng Chen, Anna Malkova, Patrick Sung, and Grzegorz Ira. (2013) Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration. Nature 502, 393-6. - URL : https://www.nature.com/articles/nature12585
연구분야 (Research Area)
- maintenance of genome stability, DNA damage repair process
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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|---|---|---|---|---|---|---|
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신혜연 | 부교수 | 강릉원주대(문학석사) 미)Western University of Health Sciences(Pharm.D) |
임상약학 | 901-8739 | hyshin@duksung.ac.kr |
| Soyeon Kim | Associate Professor | UWestern University of Health Sciences (Pharm.D) | Clinical Pharmacy |
실습약국
대표논문/연구실적 (Representative publication)
- Hye Yeon Sin. Competency Assessment Tool and Faculty Assessors for Competency-based Pharmacy Education: A Preliminary Study of Its Applications and Advantages. Korean J Clin Pharm, Vol. 31, No. 4, 2021: 1-8. - URL : https://www.ekjcp.org/journal/view.html?uid=759&&vmd=Full
- Hye Yeon Sin. Physical activity and prevalence of rheumatoid arthritis in Korean adults with prediabetes in the 2009-2013 National Health Cohort Study. Korean J Clin Pharm, Vol. 29, No. 4, 2019: 278-285. - URL : https://www.ekjcp.org/journal/view.html?doi=10.24304/kjcp.2019.29.4.278
- Hye Yeon Sin. Risk of Fracture Prevalence and Glycemic Control in Korean Older and Middle-aged Patients with Diabetes: A Retrospective Analysis of a Cohort Derived from the Korean National Health Insurance Sharing Service Database, 2009-2013. Korean J Clin Pharm, Vol. 28, No. 3, 2018: 194-203. - URL : https://www.ekjcp.org/journal/view.html?doi=10.24304/kjcp.2018.28.3.194
연구분야 (Research Area)
- Clinical Pharmacy
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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|---|---|---|---|---|---|---|
|
박희준 | 부교수 | 충남대(석,박사) 미)Purdue대(Post Doc.) |
약제학,제제공학 | 901-8589 | heejunpark@duksung.ac.kr |
| Heejun Park | Associate Professor | Chungnam National University. Ph.D. | Pharmaceutics |
약제학 연구실 (Pharmaceutical Research Lab)
본 연구실은 신약 및 개량신약 의약품의 개발을 위해 첨단의 약제학적 약물전달기술을 적용하여 다양한 제형의 제제개발 및 이의 생물약제학적 특성 평가를 위한 연구를 하고 있으며, 연구재단 개인 및 집단과제, 제약회사들과 개량신약 및 신약 개발을 위한 용역과제 및 식약처 과제에도 참여하고 있습니다.대학원때부터 제약회사 연구소에서 이루어지는 의약품 개발 과정에 참여할 수 있는 기회 뿐만 아니라 최첨단의 제약기술들에 대한 기초이론 및 응용개발에 대한 지식을 얻으실 수 있는 연구실입니다.
대표논문/연구실적 (Representative publication)
- Complexation of exenatide and cyclodextrin: An approach for the stabilization and sustained release of exenatide in PLGA microsphere : SCIE. - URL : https://doi.org/10.1016/j.carbpol.2021.118169
- Understanding Dynamics of Polymorphic Conversion during the Tableting Process Using In Situ Mechanical Raman Spectroscopy : SCIE - URL : https://doi.org/10.1021/acs.molpharmaceut.0c00460
- Correlations between surface composition and aerosolization of jet-milled dry powder inhaler formulations with pharmaceutical lubricants : SCIE - URL : https://doi.org/10.1016/j.ijpharm.2019.118504
연구분야 (Research Area)
- Nano/microparticle technologies, Dry Powder Inhaler (Pulmonary/Nasal), Lipid based Drug delivery systems, Sustained release injectable preparation, Drug polymorphism, Process analytical technology (PAT), Quality by design (QbD)
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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|---|---|---|---|---|---|---|
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송경 | 조교수 | 서울대(석사) 서울대(박사) |
병태생리학 | 901-8382 | songseoul17@duksung.ac.kr |
| Kyoung Song | Assistant Professor | Seoul National University. Ph.D. | Pathology/ protein therapeutics |
병태생리학연구실
대표논문/연구실적 (Representative publication)
- Kyoung Song, Nirmal Rajasekaran, Chaithanya Chelakkot, Hun Seok Lee, Seung-Mann Paek, Hobin Yang, Lina Jia, Hee Geon Park, Woo Sung Son, Yu-Jin Kim, Joon-Seok Choi, Hae Min Jeong, Young-Ger Suh, Hwayoung Yun, Young Kee Shin Macrosphelide A Exhibits a Specific Anti-Cancer Effect by Simultaneously Inactivating ENO1, ALDOA, and FH Pharmaceuticals (Basel). 2021 Oct 19;14(10):1060.(Co-First) - URL : https://www.mdpi.com/1424-8247/14/10/1060
- Nirmal Rajasekaran†, Kyoung Song†, Jin-Hee Lee,Yun Wei, Özgür Cem Erkin, Hunseok Lee and Young-Kee Shin Nuclear Respiratory Factor-1, a Novel SMAD4 Binding Protein, Represses TGF-β/SMAD4 Signaling by Functioning as a Transcriptional Cofactor. Int. J. Mol. Sci. 2021, 22(11)(Co-first) - URL : https://www.mdpi.com/1422-0067/22/11/5595
- Kyoung Song*, Dae Bong Moon, Na Young Kim, and Young Kee Shin*, Stability and Activity of the Hyperglycosylated Human Interferon-β R27T Variant. Sci Rep. 2020; 10: 8412. (*Co-corresponding author) - URL : https://www.nature.com/articles/s41598-020-65495-y
연구분야 (Research Area)
- Pathology/ protein therapeutics
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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|---|---|---|---|---|---|---|
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강성민 | 조교수 | 서울대(석,박사) 서울대 약대(Post Doc.) |
구조생물학 | 901-8774 | smkang@duksung.ac.kr |
| Sung-Min Kang | Assistant Professor | Seoul National University. Ph.D. | Physical Pharmacy / Structural Biology |
물리약학실
- 덕성여자대학교 약학대학 강성민 교수 연구실에서 대학원생(석사, 박사), 학부연구생, 연구원을 상시 모집중에 있습니다.Structural biology, biophysics, biochemistry, instrumental analysis를 하는 연구실로 X-ray와 NMR을 이용한 macromolecules의 삼차원 구조를 기반으로 질환 관련 표적분자의 기전 연구 및 치료제 개발 연구를 수행하고 있습니다. 약물개발에 있어 필수적인 타겟 단백질의 정제 및 삼차원 구조 규명 & 분석, 생화학/생물리 실험, 약물 screening 등을 수행하게 됩니다. 연구에 대한 열의와 관심을 지닌 생물, 미생물, 화학, 생화학, 약학관련 전공자, 제약회사 및 관련 연구직 희망자 모두 지원 가능합니다. 많은 연락 바랍니다.이메일 (smkang@duksung.ac.kr)로 간단한 자기소개와 이력서 제출 바랍니다.
대표논문/연구실적 (Representative publication)
- Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides : SCI - URL : https://academic.oup.com/nar/article/45/14/8564/3859018
- Fuctional insights into the Streptococcus pneumoniae HicBA toxin-antitoxin system based on a structural study : SCI - URL : https://academic.oup.com/nar/article/46/12/6371/5033530
- Structural and Functional Study of the Klebsiella pneumoniae VapBC Toxin-Antitoxin System, Including the Development of an Inhibitor That Activates VapC : SCI - URL : https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01118
연구분야 (Research Area)
- Physical Pharmacy / Structural Biology
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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박지현 | 조교수 | 서울대(석사) 고려대(박사) 미네소타주립대(Pharm.D) |
임상약학 | 901-8418 | pharmerpark@duksung.ac.kr |
| Ji Hyun Park | Assistant Professor | University of Minnesota Pharm.D. | Clinical Pharmacy/ Pharmacoepidemiology & Pharmacovigilance |
임상약학연구실
대표논문/연구실적 (Representative publication)
- Kang MJ, Park JH, Park S, Kim NG, Kim EY, Yu YM, Kim DY, Lee JY, Shin WG, Choi SA. Community pharmacists' knowledge, perceptions, and practices about topical corticosteroid counseling: A real-world cross-sectional survey and focus group discussions in Korea. PLoS One. 2020 Jul 29;15(7):e0236797. - DOI : 10.1371/journal.pone.0236797. PMID: 32726366; PMCID: PMC7390350. - URL : https://pubmed.ncbi.nlm.nih.gov/32726366/
- Park, J.H., Park, S. & Choi, S.A. Incidence and risk factors of spinal epidural hemorrhage after spine surgery: a cross-sectional retrospective analysis of a national database. BMC Musculoskelet Disord 21, 324 (2020). - URL : https://doi.org/10.1186/s12891-020-03337-8
- Park, J. H., Lee, K. E., Yu, Y. M., Park, Y. H., & Choi, S. A. (2019). Incidence and risk factors for venous thromboembolism after spine surgery in Korean patients. World neurosurgery, 128, e289-e307. - DOI : 10.1016/j.wneu.2019.04.140 - URL : https://pubmed.ncbi.nlm.nih.gov/31028984/
연구분야 (Research Area)
- Pharmacovigilance and pharmacoepidemiology
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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김은숙 | 조교수 | 덕성여대 (석,박사) | 생물화학 | 901-8843 | eskim19@duksung.ac.kr |
| Eun sook Kim | Assistant Professor | Duksung Women’s University. Ph.D. | Biochemistry |
세포생화학 연구실 (Cellular Biochemistry Laboratory)
본 연구실은 암세포와 암세포 주변을 둘러싸고 있는 암미세환경(Tumor Microenvironment)간의 상호작용을 연구하고 이것이 암의 성장 및 전이 과정에 미치는 영향을 연구한다. 암 생물학 및 분자세포생물학에 사용되는 다양한 기법을 활용하여 암전이를 조절하는 새로운 기전 및 타겟 단백질을 발굴하고자 한다. 최종적으로 암을 촉진시키데 기여하는 핵심 타겟을 발굴하고 이를 제어하여 암을 효과적으로 예방할 수 있는 방법을 개발하고 있다.
대표논문/연구실적 (Representative publication)
- Kim ES, Nam SM, Song HK, Lee S, Kim K, Lim HK, Lee H, Kang KT, Kwon YJ, Chun YJ, Park SY, Jung J, Moon A. CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity. Oncogene. 40(18):3245-3259, 2021 - URL : https://www.nature.com/articles/s41388-021-01758-w
- Kim ES, Kim SY, Koh M, Lee HM, Kim K, Jung J, Kim HS, Moon WK, Hwang S, Moon A. C-reactive protein binds to integrin α2 and Fcγ receptor I, leading to breast cell adhesion and breast cancer progression. Oncogene. 37(1):28-38. 2018 - URL : https://www.nature.com/articles/onc2017298
- Kim ES, Cha YJ, Ham MN, Jung JH, Kim SG, Hwang SJ, Kleemann R, Moon A. Inflammatory Lipid Sphingosine-1-phosphate Upregulates C-reactive Protein viaC/EBPb and Potentiates Breast Cancer Progression. Oncogene. Jul 3; 33(27). 3583-3593. 2014. - URL : https://www.nature.com/articles/onc2013319
연구분야 (Research Area)
- Tumor microenvironment of breast cancer
- Inflammation and breast cancer progression
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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|---|---|---|---|---|---|---|
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이진우 | 조교수 | 충북대 (석,박사) University of Oklahoma Post Doc.) |
생약학,천연물화학 | 901-8841 | jwlee22@duksung.ac.kr |
| Jin woo Lee | Assistant Professor | Chungbuk National University College of Pharmacy. Ph.D. |
Pharmacognosy Natural Products Chemistry |
천연물화학연구실, Natural Products Drug Discovery La
천연물(생약)로부터 생리활성물질을 분리정제하여 이들의 입체구조와 활성기전을 규명하는 연구를 합니다.
주요 연구는 다음과 같습니다.
- 1) 토양 진균 유래 생리활성 물질 분리 정제 및 입체 구조 규명
- 2) 식물 유래 항염증 활성 물질 분리 정제
- 3) 식물과 공생미생물의 대사체 분석
대표논문/연구실적 (Representative publication)
- in Woo Lee, Jennifer E. Collins, Karen L. Wendt, Debopam Chakrabarti, and Robert H. Cichewicz.Leveraging Peptaibol Biosynthetic Promiscuity for Next-Generation Antiplasmodial Therapeutics. J. Nat. Prod. 2021, 84, 503-517.
- Jennifer E. Collins, Jin Woo Lee, Monica J. Bohmer, Joshua D. Welden, Arash K. Arshadi, Lin Du, Robert H. Cichewicz, and Debopam Chakrabarti. Cyclic Tetrapeptide HDAC Inhibitors with Improved Plasmodium falciparum Selectivity and Killing Profile.ACS Infect. Dis. 2021, 7, 2889–2903.(Co-first)
- Jin Woo Lee, Jun Gu Kim, Jae Sang Han, Yong Beom Cho, Yu Jin Lee, Dongho Lee, Dae Hwan Shin, Jin Tae Hong, Mi Kyeong Lee, and Bang Yeon Hwang. Dianthiamides A-E, Proline-Containing Orbitides from Dianthus chinensis.Molecules. 2021, 26, 7275-7285.
연구분야 (Research Area)
- Purification and Structure elucidation of bioactive compounds from natural products
- Isolation of bioactive peptidic compounds from plants and fungi
- Natural products metabolomics analysis
| 사진 (Photo) |
이름 (Name) |
직위 (Position) |
학위 (Degree) |
전공/연구분야 (Major/Research area) |
구내전화 (Phone) |
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이혜정 | 조교수 | 연세대(박사) | 유기화학/합성화학 | 901-8842 | Hjeonglee@duksung.ac.kr |
| Lee Hyejeong | Assistant Professor | Yonsei University. Ph. D. | Organic Chemistry/Synthetic Phamaceutical Chemistry |
전이금속 촉매를 이용한 유기 합성 연구실(Transition-metal catalyzed Organic Synthesis Lab)
대표논문/연구실적 (Representative publication)
- Synthesis of N-substituted quaternary carbon centers through KOt-Bu-catalyzed aza-Michael addition of pyrazoles to cyclic enones - URL : https://doi.org/10.1039/D2OB01634F
- ynthesis and study of the physical and photovoltaic properties of novel heterolepticruthenium(II) complexes ligated with highly p-conjugated bipyridine ancillary and phenanthroline anchoring ligand for dye-sensitized solar cells - URL : https://doi.org/10.1155/2021/1847146
- Synthetic strategy to new terphenyl-type bis-pyrrole arenes starting from highly electron-deficient 4-nitroanilines with 1,4-diketones - URL : https://doi/10.3987/COM-19-14190
연구분야 (Research Area)
- Develop of novel synthetic method
- Application of transition metal-organic complexes and heterocylclic compounds
- cosmetic chemistry
