덕성여대 약학대학

교수 소개

연구실

8393(office)

8493 (Lab)

학력

주요경력

연구업적

[Studies on the Selective Syntheses of Sodium Ditelluride and Dialkyl Ditellurides], 2022, MOLECULES
[Syntheses of New Multisubstituted 1-Acyloxyindole Compounds], 2022, MOLECULES
[Reuterin 및 이의 구조적 특징과 생물학적 활성에 대한 고찰], 2022, 약 학 회 지
[An Efficient Method for Selective Syntheses of Sodium Selenide and Dialkyl Selenides], 2022, MOLECULES
[Oroxylin A와 관련 유도체 합성 및 효능에 관한 고찰], 2021, 약 학 회 지
[One-pot Synthesis of Novel Multisubstituted 1-Alkoxyindoles], 2021, Molecules
[Resveratrol과 관련 유도체 합성 및 효능에 관한 고찰], 2020, 약학회지
[An efficient and practical method for the selective synthesis of sodium diselenide and diorganyl diselenides through selenium reduction], 2020, Tetrahedron
[Coleus forskholii 의 구성성분 및 Forskolin 관련 유도체에 관한 연구], 2019, 약학회지
[Sceletium tortuosum의 구성성분 및 Mesembrine 관련 유도체에 관한 연구], 2018, 약학회지
[Synthesis and Antiproliferative Activities of 1-Hydroxyindole-2-Carboxylates], 2018, Bulletin of the Korean Chemical Society

수행과제

연구분야

[Organic Chemistry]
-Retrosynthetic analysis and total synthesis of complex natural products
-Design and synthesis of bioactive molecules; isolation and characterization of chiral compounds
-Studies on sulfur-containing heterocycles
-Indole synthesis through novel nucleophilic 1,5-additions
[Medicinal Chemistry]
-Sulfur/Selenium-containing molecules: design, synthesis, and biological evaluations
-Drug activation mechanism of anticancer agents, mitomycins: mechanistic (kinetic) studies on drug activation using solvolysis reaction
-DNA binding profiles: evaluation of the efficiency of drug to produce DNA ISC (interstrand cross-links)
[Drug development]
-Design, synthesis and application of small molecules for CNS diseases such as Parkinson’s disease and AD based on the imidazolidine scaffold.
-Application of various disulfide-containing molecules as antioxidant agens

강의과목